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Vitamin E protected cultured cortical neurons from oxidative stress-induced cell death through the activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase

✍ Scribed by Yumiko Numakawa; Tadahiro Numakawa; Tomoya Matsumoto; Yuki Yagasaki; Emi Kumamaru; Hiroshi Kunugi; Takahisa Taguchi; Etsuo Niki


Book ID
111179525
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
433 KB
Volume
97
Category
Article
ISSN
0022-3042

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Gene therapy for neurodegenerative diseases may utilize the expression of neurotrophic factors because of their potential to promote survival and regeneration of injured neuronal cells. Increasing numbers of these factors are being considered for gene transfer, but their specificity and efficacy in