2-Chlorobenzylmercapturic acid, a metabolite of the riot control agent 2-chlorobenzylidene malononitrile (CS) in the rat
β Scribed by E. C. Rietveld; L. P. C. Delbressine; T. H. J. M. Waegemaekers; F. Seutter-Berlage
- Book ID
- 105138398
- Publisher
- Springer-Verlag
- Year
- 1983
- Tongue
- English
- Weight
- 386 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0340-5761
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eChlorobenzylidene malononitrile (CS), a riot control agent, was evaluated for its possible mutagenic activity in the Ames Salmonella/mammalian microsome mutagenicity test. Five histidine-deficient (His-) mutant tester strains of Salmonella typhimurium-TA97a, TA98, TA100, TA102 and TAlOAwere used. T
The repeated dose inhalation toxicity of 2-chlorobenzylidene maloninitrile (CS) was investigated in male mice, rats, and guinea-pigs. Exposure was 1 h X day-1 for 120 days surviving animals being killed approximately 1 year after the start of exposure. Excess mortality was noted in the high dose gro