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2- and 4-Pyridones by oxidative demethylation of 2- and 4-methylpyridinium cations

✍ Scribed by Katritzky, Alan R.; Patel, Ranjan C.; Shanta, Mohammed


Book ID
111656274
Publisher
Royal Society of Chemistry
Year
1980
Weight
265 KB
Volume
0
Category
Article
ISSN
1472-7781

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Heterocyclic 4-sulfonyl-2-pyridones represent useful scaffolds for drug discovery and are also versatile synthetic building blocks. Herein we describe a novel and efficient synthesis of this heterocyclic ring system utilizing an acid mediated cyclo-condensation reaction. This synthetic method afford