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2-Aminothiophenol as building blocks for novel heterocycles

โœ Scribed by El-Shaieb, K. M.


Book ID
126519896
Publisher
Taylor and Francis Group
Year
2007
Tongue
English
Weight
136 KB
Volume
28
Category
Article
ISSN
1741-5993

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2,2,2-Trifluoroacetimidoyl chlorides 1 are much more stable than the corresponding nonfluorinated chlorides because of the deactivation for hydrolysis by the strong electronwithdrawing fluorine atom and thus useful as synthetic blocks. They react smoothly with nucleophilics such as Grignard reagent