𝔖 Bobbio Scriptorium
✦   LIBER   ✦

2-Aminopurine induced DNA repair in E. coli

✍ Scribed by Maenhaut-Michel, Geneviève ;Caillet-Fauquet, Perrine

Publisher
Springer
Year
1982
Tongue
English
Weight
549 KB
Volume
188
Category
Article
ISSN
0026-8925

No coin nor oath required. For personal study only.

✦ Synopsis

The survival of UV-irradiated lambda phages is increased when host bacteria are grown in the presence of the base analogue 2-aminopurine (2AP) before infection. This increase in survival, which we have called "2AP-reactivation" depends upon the concentration of 2AP and the time of exposure to 2AP. 2AP-reactivation can be distinguished from Weigle-reactivation in that it is not accompanied by an increase in mutagenesis, does not act on the single-stranded DNA bacteriophage phi X174, and occurs in recA and lexA bacteria. 2AP reactivation does not appear to involve known systems of recombinational repair, as it occurs in recB and recF bacteria, or excision repair, as it occurs in uvrA and uvrB bacteria. It is however dependent upon DNA polymerase I.

📜 SIMILAR VOLUMES

Inducible, error-free DNA repair in tsl
Inducible, error-free DNA repair in tsl recA mutants of E. coli
✍ Mount, David W. ;Kosel, Candace K. ;Walker, Anita 📂 Article 📅 1976 🏛 Springer 🌐 English ⚖ 445 KB

Host of cell reactivation and UV reactivation and mutagenesis of UV-irradiated phage mu were measured in tsl recAplus and tsl recA host mutants. Host cell reactivation was slightly more efficient in the tsl recA strain. Phage was UV-reactivated in the tsl recA strain with about one-half the efficien

DNA repair in E. coli strains deficient
DNA repair in E. coli strains deficient in single-strand DNA binding protein
✍ Whittier, Robert F. ;Chase, John W. 📂 Article 📅 1981 🏛 Springer 🌐 English ⚖ 765 KB

Weigle reactivation and mutagenesis have been found to be defective in strains of E. coli deficient in single-strand DNA binding protein (SSB). These defects parallel those previously found in prophage induction and amplification of recA protein synthesis in ssb- strains. Together, these results dem

Mutagenic DNA repair in Escherichia coli
Mutagenic DNA repair in Escherichia coli
✍ Doubleday, O. P. ;Bridges, B. A. ;Green, M. H. L. 📂 Article 📅 1975 🏛 Springer 🌐 English ⚖ 618 KB

The photoreversibility of UV-induced mutations to Trp+ in strain Escherichia coli WP2 uvrA trp (unable to excise pyrimidine dimers) was lost at different rates during incubation in different media. In Casamino acids medium after a short initial lag, photoreversibility was lost over about one generat