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2-Amino-5,6-dihydro-1,3-oxazines. The Reduction of Carboxylic Esters with Sodium Borohydride 1

✍ Scribed by Meschino, Joseph A.; Bond, Carol H.


Book ID
127187211
Publisher
American Chemical Society
Year
1963
Tongue
English
Weight
621 KB
Volume
28
Category
Article
ISSN
0022-3263

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Reduction of 5,6-dihydro-2H-1,3-oxazines
✍ JosΓ© Barluenga; JesΓΊs Joglar; Francisco J. GonzΓ‘lez; Santos Fustero πŸ“‚ Article πŸ“… 1989 πŸ› Elsevier Science 🌐 French βš– 252 KB

The reduction of 5,6-dihydro-211-1,3-oxazines 2 is described for the first time.This reaction allows the diastereoselective synthesis of 1,3-amino alcohols 3 and 4 with three and four chiral centers.