✦ LIBER ✦

2-Amino-3-(1-(4-(4-(2-methoxyphenyl) piperazine-1-yl)butyl)-1H-1,2,3-triazol-4-yl) propanoic acid: synthesized, 99mTc-tricarbonyl labeled, and bioevaluated as a potential 5HT1A receptor ligand

✍ Scribed by Leila Hassanzadeh; Mostafa Erfani; Seyed Esmaeil Sadat Ebrahimi

Book ID: 115558904
Publisher: John Wiley and Sons
Year: 2012
Tongue: French
Weight: 342 KB
Volume: 55
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.2953

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

N-[3-[4-(2-methoxyphenyl) piperaziny-1-y

N-[3-[4-(2-methoxyphenyl) piperaziny-1-yl]propyl]cyclam: synthesized as a potential 5-HT1A receptor ligand and labelled with 99mTc-nitrido core

✍ Fenglong Wang; Xuebin Wang; Shuye Yang; Jian Liu; Xianzhong Zhang 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 French ⚖ 130 KB

## Abstract This paper reports the synthesis of new potential 5‐HT~1A~ receptor ligand __N__‐[3‐[4‐(2‐methoxyphenyl)piperaziny‐1‐yl]propyl]cyclam (MPPC) and radiolabelling of it with ^99m^Tc‐nitrido core. The novel neutral complex ^99m^TcN‐MPPC combines 1,4,8,11‐tetraazacyclotetradecane (cyclam) li

Rearrangement of 2-(2,5-Dioxopyrrolidin-

Rearrangement of 2-(2,5-Dioxopyrrolidin-1-yl)guanidine: An Efficient Synthesis and Structure of 3-(5-Amino-1H-1,2,4-triazol-3-yl)propanoic Acid and Derivatives

✍ M. Chernyshev, Victor; V. Chernysheva, Anna; A. Starikova, Zoya 📂 Article 📅 2010 🏛 Japan Institute of Heterocyclic Chemistry 🌐 English ⚖ 990 KB

A Facile Synthesis of Bis(4-amino-5-merc

A Facile Synthesis of Bis(4-amino-5-mercapto-1,2,4-triazol-3-yl)alkanes and Bis(5-mercapto-4H-1,2,4-triazol-3-yl)alkanes

✍ Xu, Peng-Fei; Sun, Xiao-Wen; Zhang, Lin-Mei; Zhang, Zi-Yi 📂 Article 📅 1999 🏛 Science Reviews 2000 Ltd 🌐 English ⚖ 97 KB

Synthesis, in vitro and in vivo evaluati

Synthesis, in vitro and in vivo evaluation of [O-methyl-11C] 2-{4-[4-(3-methoxyphenyl)piperazin-1-yl]-butyl}-4-methyl-2H-[1,2,4]-triazine-3,5-dione: A novel agonist 5-HT1A receptor PET ligand

✍ Jaya Prabhakaran; Ramin V. Parsey; Vattoly J. Majo; Shu-Chi Hsiung; Matthew S. M 📂 Article 📅 2006 🏛 Elsevier Science 🌐 English ⚖ 200 KB

Structural and spectroscopic characteriz

Structural and spectroscopic characterization of a novel potential chemotherapeutic agent 3-(1-adamantyl)-1-{[4-(2-methoxyphenyl)piperazin-1-yl]methyl}-4-methyl-1H-1,2,4-triazole-5(4H)-thione by first principle calculations

✍ Ali A. El-Emam; Abdul-Malek S. Al-Tamimi; Khalid A. Al-Rashood; Hriday N. Misra; 📂 Article 📅 2012 🏛 Elsevier Science 🌐 English ⚖ 946 KB

2-[4-(o-methoxyphenyl)piperazin-1-ylmeth

2-[4-(o-methoxyphenyl)piperazin-1-ylmethyl]-1,3-dioxoperhydroimidazo[1,5-a]pyridine as a new selective 5-HT1A receptor ligand

✍ María L. López-Rodríguez; MaJosé Morcillo; MaLuisa Rosado; Bellinda Benhamu; Ant 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 246 KB

A series of 2-[~-(4-arylpiperazin-1-yl)aikyl]-1,3-dioxoperhydroimidazo[ 1,5-a]pyridine derivatives was prepared and evaluated for affinity at 5-HT~A and ct I receptors. The most promising analogue Ira bound at 5-HT~A sites with nanomolar affinity (/~.=31.7) and high selectivity over ~, D2 and 5-HT2A