𝔖 Bobbio Scriptorium
✦   LIBER   ✦

2-Alkyl 1-(4′-benzhydrazide)aminomethylbenzimidazoles as MAO Inhibitors

✍ Scribed by Surendra S. Parmar; R. S. Misra; A. Chaudhari; T. K. Gupta

Book ID
102408333
Publisher
John Wiley and Sons
Year
1972
Tongue
English
Weight
273 KB
Volume
61
Category
Article
ISSN
0022-3549

No coin nor oath required. For personal study only.

✦ Synopsis

I J 2-Alkyl 1-(4'-benzhydrazide)aminomethylbenzimidazoles were synthesized and evaluated for their MA0 inhibitory property, using kynuramine, tyramine, and 5-hydroxytryptamine as substrates. Anticonvulsant activity exhibited by these benzimidmole hydrazides against pentylenetetrazol-induced seizures was found to be unrelated to the MA0 inhibitory ability of these compounds.

📜 SIMILAR VOLUMES

Synthesis of 1-alkyl-2,3-dihydro-2-(4-py
Synthesis of 1-alkyl-2,3-dihydro-2-(4-pyridinyl)-1H-isoindoles as potential selective serotonin reuptake inhibitors
✍ Kevin J. Kapples; Gregory M. Shutske 📂 Article 📅 1997 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 305 KB

## Abstract Two 2,3‐dihydro‐2‐(4‐pyridinyl)‐1__H__‐isoindoles 2a,b have been synthesized by the reaction of isoindoline with 4‐chloropyridines. In addition, a number of 1‐alkyl‐2,3‐dihydro‐2‐(4‐pyridinyl)‐1__H__‐isoindoles 2c‐h were obtained from 2‐(4‐pyridinyl)phthalimide (5). The addition of alky