2-(4-Chlorophenyl)-3-methyl-N-(thiazol-2-yl)butanamide
✍ Scribed by Zhao, Jin-Hao ;Cheng, Jing-Li ;Huang, Yan-Kun ;Zhu, Guo-Nian
- Publisher
- International Union of Crystallography
- Year
- 2006
- Tongue
- English
- Weight
- 202 KB
- Volume
- 62
- Category
- Article
- ISSN
- 1600-5368
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📜 SIMILAR VOLUMES
In the title compound, C 16 H 13 Cl 3 N 6 O 3 S, the substituted triazole ring is bound via a methylene bridge to a chlorothiazole unit. There is evidence for significant electron delocalization in the triazolyl system. Both intra-and intermolecular hydrogen bonds are found in the structure.
The asymmetric unit of the title compound, C 18 H 10 Cl 2 N 2 S 4 , consists of one full molecule and two half molecules, which are completed by twofold rotation symmetry.
In the title compound, C 18 H 14 ClN 3 O 2 S 2 , the thiazolidine ring adopts an envelope conformation. There are intermolecular C-HÁ Á ÁO interactions, forming centrosymmetric dimers.
The title compound, C 17 H 12 ClN 5 S, has been synthesized as a potent anticancer agent. The dihedral angle between the thiazole and triazole rings is 85.9 (2) . There are intermolecular N-HÁ Á ÁN and C-HÁ Á ÁCl interactions in the crystal structure.