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1-[(2-Chloro­thia­zol-5-yl)meth­yl]-N′-[2-(2,4-dichloro­phen­oxy)acet­yl]-5-methyl-1H-1,2,3-triazole-4-carbohydrazide

✍ Scribed by Yan, Man ;Shi, De-Qing

Publisher
International Union of Crystallography
Year
2007
Tongue
English
Weight
225 KB
Volume
63
Category
Article
ISSN
1600-5368

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✦ Synopsis

In the title compound, C 16 H 13 Cl 3 N 6 O 3 S, the substituted triazole ring is bound via a methylene bridge to a chlorothiazole unit. There is evidence for significant electron delocalization in the triazolyl system. Both intra-and intermolecular hydrogen bonds are found in the structure.

📜 SIMILAR VOLUMES

4-(4-Chloro­phen­yl)-N-phenyl-5-(1H-1,2,
4-(4-Chloro­phen­yl)-N-phenyl-5-(1H-1,2,4-triazol-1-yl)thia­zol-2-amine
✍ Shao, Ling ;Zhou, Xin ;Fang, Jian-Xin 📂 Article 📅 2005 🏛 International Union of Crystallography 🌐 English ⚖ 193 KB

The title compound, C 17 H 12 ClN 5 S, has been synthesized as a potent anticancer agent. The dihedral angle between the thiazole and triazole rings is 85.9 (2) . There are intermolecular N-HÁ Á ÁN and C-HÁ Á ÁCl interactions in the crystal structure.

O,O-Diethyl [({1-[(2-chloro­thia­zol-5-y
O,O-Diethyl [({1-[(2-chloro­thia­zol-5-yl)meth­yl]-5-methyl-1H-1,2,3-triazol-4-yl}carbon­yloxy)phenyl­meth­yl]phospho­nate
✍ Chen, Xiao-Bao ;Shi, De-Qing 📂 Article 📅 2006 🏛 International Union of Crystallography 🌐 English ⚖ 232 KB

In the title compound, C 19 H 22 ClN 4 O 5 PS, the P atom adopts a distorted tetrahedral configuration. Intra-and intermolecular C-HÁ Á ÁO hydrogen bonds, together with weak C-HÁ Á Á hydrogen bonding and strongstacking interactions, stabilize the crystal structure.