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2-(3,5-Dihydroxyphenyl)-6-Hydroxybenzothiazole Arrests Cell Growth and Cell Cycle and Induces Apoptosis in Breast Cancer Cell Lines

✍ Scribed by Rajabi, Mehdi

Book ID: 127086450
Publisher: Mary Ann Liebert
Year: 2012
Tongue: English
Weight: 190 KB
Volume: 31
Category: Article
ISSN: 1044-5498
DOI: 10.1089/dna.2011.1363

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## Abstract 2‐Methoxyestradiol, a well‐known nonpolar endogenous metabolite of 17β‐estradiol, has been shown to selectively induce apoptosis in a number of cancer cell lines, but not in normal cells. The mechanism of 2‐methoxyestradiol‐induced apoptosis appears to vary considerably in different cel