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A novel organoselenium compound induces cell cycle arrest and apoptosis in prostate cancer cell lines

✍ Scribed by Changjin Shi; Lizhang Yu; Fengguang Yang; Jun Yan; Huihui Zeng


Book ID
116286950
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
299 KB
Volume
309
Category
Article
ISSN
0006-291X

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## Abstract α‐Lipoic acid is a naturally‐occurring co‐factor found in a number of multi‐enzyme complexes regulating metabolism. We report here that α‐lipoic acid induces hyperacetylation of histones in vivo and has differential effects on the growth and viability of normal versus transformed cell l