## Abstract Aberrant constitutive expression of the NF‐κB c‐Rel and RelA subunits in breast cancer cells was shown to promote their survival. Recently, we demonstrated that aggressive breast cancers constitutively express high levels of the RelB subunit, which promotes their more invasive phenotype
1α,25-Dihydroxyvitamin D3inhibits the invasive potential of human breast cancer cellsin vitro
✍ Scribed by Christina Mørk Hansen; Thomas L. Frandsen; Nils Brünner; Lise Binderup
- Publisher
- Springer
- Year
- 1994
- Tongue
- English
- Weight
- 752 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0262-0898
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
The replication of several human and animal cancer cell lines is regulated in vitro and in vivo by 1,25-dihydroxyvitamin D3 I 1 ,25-(OH),D3], the hormonally active form of vitamin Uj. We have examined the effects of concentrations of 1 ,25-(OH)2D3, which inhibit cellular replication, on the cell-cyc
## Abstract The differentiating and antitumor activities of 1α,25‐dihydroxyvitamin D~3~ (1α,25(OH)~2~D~3~) in vitro and 1α‐hydroxyvitamin D~3~ (1α(OH)D~3~) in vivo were studied with a human osteosarcoma cell line (OST strain). Antitumor activity was estimated with the use of 3‐(4,5‐dimethylthiazol)