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1α,25-Dihydroxyvitamin D3 Modulates CYP2R1 Gene Expression in Human Oral Squamous Cell Carcinoma Tumor Cells

✍ Scribed by Sundaram, Kumaran; Sambandam, Yuvaraj; Tsuruga, Eichi; Wagner, Carol L.; Reddy, Sakamuri V.

Book ID
121558492
Publisher
Springer-Verlag
Year
2014
Tongue
English
Weight
391 KB
Volume
5
Category
Article
ISSN
1868-8497

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✍ Louis G. Jenis; Jane B. Lian; Gary S. Stein; Dr. Daniel T. Baran 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 563 KB

## Abstract 1α,25‐Dihydroxyvitamin D~3~ exerts rapid nongenomic effects on rat osteoblast‐like cells independent of the classic nuclear receptor. These effects include changes in phospholipid metabolism and cell calcium. Intracellular calcium itself has been proposed to regulate intracellular pH in