1,x-Elimination Reactions: Extending the Limits of a Classical Organic Reaction
✍ Scribed by Christian Werner; Henning Hopf; Ina Dix; Peter Bubenitschek; Peter G. Jones
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 461 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0947-6539
No coin nor oath required. For personal study only.
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## A Concise Asymmetric Synthesis of the Pheromone 1-Methylcyclohex-2-enol (IV) via a "Merged Substitution-Elimination Reaction". -The title compound (III) is prepared from cyclohexene (I) via Sharpless asymmetric dihydroxylation using AD-mix-β, tosylation and an unexpected elimination reaction.
## Abstract Kinetics of elimination of methanesulfonic acid from 1,2‐diphenylethylmethane sulfonate and its 1‐__p__‐methylphenyl‐ and 1‐__p__‐chlorophenyl‐substituted derivatives is studied. The results show that the elimination reaction is unimolecular (E1) as reported in the case of 1‐chloro‐1‐(4