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(1S,3S,5S)-2-Amino-3-methoxymethyl-2-azabicyclo [3.3.0]octan: SAMBO — ein neuer chiraler Hilfsstoff

✍ Scribed by Martens, Jürgen ;Lübben, Stefan

Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
470 KB
Volume
1990
Category
Article
ISSN
0947-3440

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✦ Synopsis

(1__S__,3__S__,5__S__)‐2‐Amino‐3‐methoxymethyl‐2‐ azabicyclo[3.3.0]octane: SAMBO — a New Chiral Auxiliar

(1__S__,3__S__,5__S__)‐2‐Amino‐3‐methoxymethyl‐2‐azabicyclo[3.3.0] octane (SAMBO) (8) was synthesized with an overall yield of 48% starting from the α‐amino acid derivative benzyl (1__S__,3__S__,5__S__)‐2‐azabicyclo[3.3.0]octane‐3‐carboxylate (1) by a six‐step procedure.

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