The title compound, C 27 H 34 ClNO, was synthesized by a direct condensation reaction. The molecule has three chiral centres, which exhibit R, S and R absolute configurations, respectively. Two six-membered rings with different conformations coexist in the structure and they form a trans ring juncti
[(1R,4aS)-7-Isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl](piperidin-1-yl)methanone
✍ Scribed by Rao, Xiao-Ping ;Song, Zhan-Qian ;Jia, Wei-Hong ;Shang, Shi-Bin
- Publisher
- International Union of Crystallography
- Year
- 2007
- Tongue
- English
- Weight
- 856 KB
- Volume
- 63
- Category
- Article
- ISSN
- 1600-5368
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## Synthesis of Functionalized 4a-Methyl-1,2,3,4,4a,9,10,10aoctahydrophenanthrenes. -Two approaches are developed for the preparation of the title compounds [cf. (IV) and (IX)/(X)] which represent the skeleton of a widespread family of diterpenes. -(DYKER, GERALD;
The title compound, C 20 H 16 O 6 , was synthesized by the reaction of 4-methoxybenzaldehyde with triacetic acid lactone in ethylene glycol catalyzed by KF-alumina. The pyran ring adopts a boat conformation and the benzene ring is perpendicular to the mean plane through the fused ring system.
The title diterpene, C 19 H 24 O 4 , which was totally synthesized from geranic acid, has the tricyclic backbone of a podocarpic diterpene. The skeleton does not show a planar configuration, but is distinctly bent.