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1H,13C, and15N NMR assignments of aDrosophilaHedgehog autoprocessing domain

✍ Scribed by Jian Xie, Zhenming Du, Brian Callahan, Marlene Belfort…

Book ID: 120903211
Publisher: Springer-Verlag
Year: 2013
Tongue: English
Weight: 449 KB
Volume: 8
Category: Article
ISSN: 1874-2718
DOI: 10.1007/s12104-013-9500-8

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## Abstract Phenazopyridine hydrochloride (**1**), a drug in clinical use for many decades, and some derivatives were studied by one‐ and two‐dimensional ^1^H, ^13^C and ^15^N NMR methodology. The assignments, combined with DFT calculations, reveal that the preferred protonation site of the drug is