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1H spectroscopic imaging using a spectral-spatial excitation pulse

✍ Scribed by Daniel Spielman; Craig Meyer; Albert Macovski; Dieter Enzmann

Book ID
102952327
Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
721 KB
Volume
18
Category
Article
ISSN
0740-3194

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✦ Synopsis

Abstract

Excellent water suppression is required to perform in vivo ^1^H spectroscopic experiments. However water suppression is difficult due to both B~0~ and RF inhomogeneities. These inhomogeneities are particularly troublesome in spectroscopic imaging experiments where water suppression is required throughout some large region of interest. In this paper, we propose the use of spectral‐spatial excitation pulses for such experiments. These two‐dimensional pulses are shown to provide water suppression that is insensitive to a range of B~0~ and RF variations while simultaneously providing spatial localization. Experimental results including images (with voxel volumes ranging from 3.4 to 1.5 cc) of various brain metabolites from both a normal volunteer and a patient with a metastatic lung carcinoma are presented. © 1991 Academic Press. Inc.

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