1H NMR, UV and Circular Dichroism Study of Inclusion Complex Formation between the 5-Lipoxygenase Inhibitor Zileuton and β- and γ-Cyclodextrins
✍ Scribed by Cotta Ramusino, M. ;Bartolomei, M. ;Gallinella, B.
- Book ID
- 111716229
- Publisher
- Springer Netherlands
- Year
- 1998
- Tongue
- English
- Weight
- 106 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0923-0750
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The inclusion complexes of 2-, 3-, and 4-hydroxypyridines with @cyclodextrin in aqueous solution have been studied by high field 'H NMR. All complexes showed a 1: 1 stoichiometry and the apparent association constants reflected the polarity of the guest compounds in a qualitative fashion. The inclus
## Abstract The host–guest complex formed in aqueous solution between γ‐cyclodextrin (γ‐CD) and the macrocyclic paramagnetic shift reagent TmDOTP^5−^ was examined by NMR spectroscopy. Paramagnetic lanthanide‐induced shifts (LIS) and spin‐lattice relaxation rate enhancements in the proton resonances