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1H-NMR Investigation of the Binding of 2-Methylnaphthalene to α-Cyclodextrin in D2O Solutions

✍ Scribed by Sanyo Hamai; Hiroshi Ikeda; Akihiko Ueno


Book ID
110257120
Publisher
Springer Netherlands
Year
1998
Tongue
English
Weight
184 KB
Volume
31
Category
Article
ISSN
0923-0750

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Elevated levels of zinc 2+ and copper 2+ are found chelated to the amyloid-beta-peptide (Ah) in isolated senile plaque cores of Alzheimer's disease (AD) patients. However, the precise residues involved in Zn 2+ ligation are yet to be established. We have used 1 H NMR and CD to probe the binding of Z