H-NMR Structural Analysis of Ethidium Bromide Complexation with Self -Complementary Deoxytetranucleotides 5'and 5'-d (TpGpCpA) in Aqueous Solution d (APCPGPT) 9 5 ' 4 (APGPCPT) 9 Complexation qf the trypanocidal drug, ethidium bromide (EB) , and the se!Pcomplementary deoxytetrarihonucleoside tripho
1H NMR determination of the self-association of an acridine homodimer and its complexation with ethidium bromide in aqueous solution
β Scribed by M.P. Evstigneev; V.P. Evstigneev; D.B. Davies
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 342 KB
- Volume
- 784
- Category
- Article
- ISSN
- 0022-2860
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The thermodynamical parameters (free energy, enthalpy, and entropy) of complex formation between ethidium bromide and single-stranded and double-stranded tetranucleotides of different base sequence [5-d(TpGpCpA), 5-d(ApCpGpT), and 5-d(ApGpCpT)] have been determined from the temperature dependencies
## Abstract The ^1^H NMR spectrum of chlorpromazine hydrochloride was fully assigned at 400 MHz. Similarly, the ^13^C NMR spectrum was assigned unambiguously using twoβdimensional NMR. Measurements of chemical shift as a function of concentration in D~2~O showed appreciable changes of shift of both