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1H NMR as a non-invasive method of studying metabolism in vivo

✍ Scribed by S.R. Williams; D.G. Gadian; E. Proctor

Publisher
Elsevier Science
Year
1988
Weight
79 KB
Volume
39
Category
Article
ISSN
0883-2889

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## Abstract Intrastriatal injection of quinolinic acid (QA) provides an animal model of Huntington disease. In vivo ^1^H NMR spectroscopy was used to measure the neurochemical profile non‐invasively in seven animals 5 days after unilateral injection of 150 nmol of QA. Concentration changes of 16 me