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Tumor size dependent changes in a murine fibrosarcoma: Use of in vivo31P NMR for non-invasive evaluation of tumor metabolic status

✍ Scribed by Paul G Okunieff; Jason A Koutcher; Leo Gerweck; Eric Mcfarland; Bernard Hitzig; Muneyasu Urano; Thomas Brady; Leo Neuringer; Herman D Suit

Publisher: Elsevier Science
Year: 1986
Tongue: English
Weight: 863 KB
Volume: 12
Category: Article
ISSN: 0360-3016
DOI: 10.1016/0360-3016(86)90038-6

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## Abstract Uncertainty regarding the intracellular/extracellular distribution of inorganic phosphate (__P__~i~) in tumors has raised concerns that pH calculated from the tumor __P__~i~ chemical shift may not accurately represent the intracellular pH (pH~in~). This issue was addressed in subcutaneo