1H-1,2,4-Triazol-3-yl-anilines: Novel Potent Inhibitors of Vascular Endothelial Growth Factor Receptors 1 and 2
โ Scribed by Alexander S. Kiselyov; Evgueni Piatnitski; Daniel Milligan; Xiaohu Ouyang
- Book ID
- 111368413
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 193 KB
- Volume
- 69
- Category
- Article
- ISSN
- 1747-0277
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract Starting from the known epoxy alcohol (I), a new strategy for the synthesis of the potent fungicide (IX) in multigram quantities is developed.
## Abstract magnified image Oneโpot reaction of 3โarylโ5โmethylโ1,3,4โoxadiazolinโ2โones **1aโg** with ethanolamine yielded the 4โ(2โhydroxyethyl)โ2โarylโ5โmethylโ2,4โdihydroโ3__H__โ1,2,4โtriazolinโ3โones **2aโg** which were converted to the azido compounds **6aโg**. These azides on 1,3โdipolar cy