In this study sequential 1H and 19F magnetic resonance imaging methods were used to map the distribution of fluorinated compounds in vivo. An intravenously administered emulsion of perfluorooctylbromide (PFOB), an agent known to localize in the reticuloendothelial system, was detected in the liver a
19F magnetic resonance imaging
β Scribed by G.N Holland; P.A Bottomley; W.S Hinshaw
- Publisher
- Elsevier Science
- Year
- 1977
- Weight
- 574 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0022-2364
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This work demonstrates the feasibility of generating fluorine NMR images at a very low magnetic field of 0.015 T by making use of the Overhauser enhancement of (19)F NMR signal brought about by a stable, water-soluble, narrow-line paramagnetic contrast agent. The enhancement in the (19)F NMR images