1943 PROSTATE SPECIFIC ANTIGEN DENSITY VELOCITY ON DUTASTERIDE HELPS PREDICT NEGATIVE PROSTATE BIOPSY: ANALYSIS OF THE REDUCE TRIAL
β Scribed by Maddox, Michael; Renzulli, Joseph; Golijanin, Dragan; Elsamra, Sammy; Somerville, Matthew; Cohen, Steven
- Book ID
- 122492854
- Publisher
- Lippincott Williams and Wilkins
- Year
- 2013
- Tongue
- English
- Weight
- 97 KB
- Volume
- 189
- Category
- Article
- ISSN
- 0022-5347
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## Abstract ## BACKGROUND. A correlation between prostate specific antigen (PSA) level and positive prostate biopsy rate was established in an era when biopsy practice patterns were different from what they are today. We evaluated if changes in biopsy practice patterns have affected the ability of
Study Type β Diagnostic (exploratory cohort) Level of Evidenceβ2b **What's known on the subject? and What does the study add?** Due to sampling error, the Gleason score of clinically localized prostate cancer is frequently underestimated at the time of initial biopsy. Given that this may lead to