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19.2 Differential expression of sodium pump isoforms in hypertension

✍ Scribed by H. Weber; G. Wozniak; I.H. Akintürk; F.W. Hehrlein; G. Scheiner-Bobis


Book ID
117684510
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
118 KB
Volume
5
Category
Article
ISSN
0967-2109

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The ENA2 gene encoding a P-type ATPase involved in Na+ and Li+ effluxes in Saccharomyces cerevisiae has been isolated. The putative protein encoded by ENA2 differs only in thirteen amino acids from the protein encoded by ENA1/PMR2. However, ENA2 has a very low level of expression and for this reason