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Differential expression of two genes encoding isoforms of the ATPase involved in sodium efflux in Saccharomyces cerevisiae

✍ Scribed by Garciadeblas, Blanca ;Rubio, Francisco ;Quintero, Francisco J. ;Bañuelos, María A. ;Haro, Rosario ;Rodríguez-Navarro, Alonso

Publisher
Springer
Year
1993
Tongue
English
Weight
703 KB
Volume
236-236
Category
Article
ISSN
0026-8925

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✦ Synopsis

The ENA2 gene encoding a P-type ATPase involved in Na+ and Li+ effluxes in Saccharomyces cerevisiae has been isolated. The putative protein encoded by ENA2 differs only in thirteen amino acids from the protein encoded by ENA1/PMR2. However, ENA2 has a very low level of expression and for this reason did not confer significant Li+ tolerance on a Li+ sensitive strain. ENA1 and ENA2 are the first two units of a tandem array of four highly homologous genes with probably homologous functions.

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