19-Norsteroids. Preparation of acetates of 5α-halo-6β,19-oxidoandrostan-3β-ol-17-one
✍ Scribed by B. I. Maksimov; F. A. Lur'i; N. V. Samsonova; L. S. Morozova
- Book ID
- 112397672
- Publisher
- Springer
- Year
- 1970
- Tongue
- English
- Weight
- 418 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0091-150X
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## Abstract Photosensitized oxygenation of 11β‐chloro‐17α‐19‐norpregn‐4‐en‐20‐yn‐17‐ol yields, aft́er reduction of the initially formed hydroperoxides, 11β‐chloro‐17α‐19‐norpregn‐3‐en‐20‐yne‐5α,17‐diol as the major product and 11β‐chloro‐17α‐19‐norpregn‐5‐en‐20‐yne‐4β,17‐diol as a minor product.
## Abstract 6β‐Iodomethyl‐19‐norcholest‐5(10)‐en‐3α‐ol (VI) was synthesized by the homoallylic rearrangement of 19‐iodocholest‐5‐en‐3α‐ol (V), which was obtained by the hydrolysis of 19‐iodocholest‐5‐en‐3α‐ol acetate derived from the displacement of cholest‐5‐ene‐3α,19‐diol 3‐acetate 19‐toluene‐p‐s