[18F]Fluoroethylflumazenil: a novel tracer for PET imaging of human benzodiazepine receptors
✍ Scribed by Gerhard Gründer; Thomas Siessmeier; Christian Lange-Asschenfeldt; Ingo Vernaleken; Hans-Georg Buchholz; Peter Stoeter; Alexander Drzezga; Hartmut Lüddens; Frank Rösch; Peter Bartenstein
- Publisher
- Springer
- Year
- 2001
- Tongue
- English
- Weight
- 138 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0340-6997
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract The involvement of gamma amino butyric acid (GABA) receptors in a variety of neurological and psychiatric diseases has promoted the development and use of radiolabelled benzodiazepines (BZ) for brain imaging by PET. However, these radioligands are unable to distinguish between the vario
## Abstract [^18^F]SPA‐RQ is an effective radioligand for imaging brain neurokinin type‐1 (NK~1~) receptors in clinical research and drug discovery with positron emission tomography. For the automated regular production of [^18^F]SPA‐RQ for clinical use in the USA under an IND we chose to use a mod
We used [18F]cyclofoxy (CF), a potent opiate antagonist with affinity for mu and kappa receptors, and the Scanditronix PC1024-7B PET scanner to study 14 patients with complex partial seizures (CPS), and 14 normal controls. Epileptic foci were localized by prolonged EEG-video monitoring. EEG was reco