18F-labelled cardiac PET tracers: selected probes for the molecular imaging of transporters, receptors and proteases

Fluorine-18 labeling of 6,7-disubstitute

Fluorine-18 labeling of 6,7-disubstituted anilinoquinazoline derivatives for positron emission tomography (PET) imaging of tyrosine kinase receptors: synthesis of 18F-Iressa and related molecular probes

✍ Yann Seimbille; Michael E. Phelps; Johannes Czernin; Daniel H. S. Silverman 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 French ⚖ 157 KB

Inhibitors of tyrosine kinase enzymatic activity represent a promising new class of antineoplastic agents. Although clinical studies performed over the last decade give more insight on the potential therapeutic applications of such drugs, identification of the individual patients who might benefit f