In some psychiatric disorders 5-HT 2A receptors play an important role. In order to investigate those in vivo there is an increasing interest in obtaining a metabolically stable, subtype selective and high affinity radioligand for receptor binding studies using positron emission tomography (PET). Co
18F-Labeling and evaluation of novel MDL 100907 derivatives as potential 5-HT2A antagonists for molecular imaging
✍ Scribed by Fabian Debus; Matthias M. Herth; Markus Piel; Hans-Georg Buchholz; Nicole Bausbacher; Vasko Kramer; Hartmut Lüddens; Frank Rösch
- Book ID
- 116799416
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 932 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0969-8051
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## Abstract In psychiatric disorders such as anxiety, depression and schizophrenia, 5‐HT~2A~ receptors play an important role. In order to investigate them __in vivo__ there is an increasing interest in selective and high‐affinity radioligands for receptor binding studies using positron emission to
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