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189 Cigarette Smoke and Benzo(a)pyrene-induced Changes in Colon Cancer Cells – Role of Phospholipase A2

✍ Scribed by S.K. Sharma; S.K. Yadav; G. Kaushik; C.M. Pathak; S.V. Rana; K.L. Khanduja


Book ID
117662724
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
55 KB
Volume
48
Category
Article
ISSN
0959-8049

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A candidate murine tumor-suppressor gene, Mom1, has been identified as the secretory phospholipase A2 (GDB nomenclature: PLA2G2A) gene. Evidence suggests that PLA2G2A functions as a tumor-suppressor because mice lacking PLA2G2A expression demonstrate increased colonic polyposis. The human homologue