186 Dasatinib blocks cetuximab- and radiation-induced nuclear translocation of the epidermal growth factor receptor in head and neck squamous cell carcinoma
โ Scribed by C. Li; M. Iida; E.F. Dunn; T.M. Brand; C.R. Peet; D.L. Wheeler
- Book ID
- 119602867
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 44 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1359-6349
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract Noninvasive imaging of the epidermal growth factor receptor (EGFR) in headโandโneck squamous cell carcinoma could be of value to select patients for EGFRโtargeted therapy. We assessed dose optimization of ^111^IndiumโDTPAโcetuximab (^111^Inโcetuximab) for EGFR imaging in a headโandโneck
## Abstract ## Background Cumulative evidence implicates the epidermal growth factor receptor (EGFR) as an important therapeutic target in head and neck squamous cell carcinoma (HNSCC). The basis for the lack of correlation between EGFR expression in the HNSCC tumor and clinical responses to EGFR