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17β-estradiol positively modulates GH signaling in human osteoblast-like cells

✍ Scribed by Isabella Villa; Simona Bolamperti; Emanuela Mrak; GianLuigi Moro; Gianfranco Fraschini; Francesca Guidobono; Alessandro Rubinacci


Book ID
116322826
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
69 KB
Volume
46
Category
Article
ISSN
8756-3282

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It is well known that 17 beta-estradiol (E2) and 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) have important roles in bone metabolism. This study was undertaken to examine E2 regulation of 1,25(OH)2D3 receptor (VDR) expression and the biological action of 1,25(OH)2D3 in human osteoblast-like cells. When h