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17β-Estradiol facilitatory action on GH signaling in human osteoblast-like cells occurs via modulation of SOCS proteins

✍ Scribed by S. Bolamperti; I. Villa; E. Mrak; P. Sirtori; G. Fraschini; A. Rubinacci; F. Guidobono


Book ID
116324359
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
68 KB
Volume
48
Category
Article
ISSN
8756-3282

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It is well known that 17 beta-estradiol (E2) and 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) have important roles in bone metabolism. This study was undertaken to examine E2 regulation of 1,25(OH)2D3 receptor (VDR) expression and the biological action of 1,25(OH)2D3 in human osteoblast-like cells. When h