17alpha;-Hydroxy-25-fluorovitamin D 3 : a potent analog of 1α,25-dihydroxyvitamin D 3
✍ Scribed by Napoli, Joseph L.; Fivizzani, Mary A.; Schnoes, Heinrich K.; DeLuca, Hector F.
- Book ID
- 126825438
- Publisher
- American Chemical Society
- Year
- 1978
- Tongue
- English
- Weight
- 653 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0006-2960
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📜 SIMILAR VOLUMES
In this communication we describe the synthesis of \(1 \alpha, 25\)-dihydroxyvitamin \(\mathrm{D}_{3}\) - \(3 \beta\)-bromoacetate \(\left[1,25(\mathrm{OH})_{2}-\mathrm{BE}\right]\), an analog of \(1 \alpha, 25\)-dihydroxyvitamin \(\mathrm{D}_{3}\left[1,25(\mathrm{OH})_{2} \mathrm{D}_{3}\right]\), a
## Abstract The active form of vitamin D~3~, 1,25(OH)~2~D~3~, is known, besides its classical effects on calcium and bone, for its pronounced immunomodulatory effects that are exerted both on the antigen‐presenting cell level as well as directly on the T lymphocyte level. In animal models, these im