26,26,26,27,27,27-Hexafluoro-1,25-dihydroxyvitamin D3: A highly potent, long-lasting analog of 1,25-dihydroxyvitamin D3
โ Scribed by Yoko Tanaka; Hector F. DeLuca; Yoshiro Kobayashi; Nobuo Ikekawa
- Book ID
- 115706033
- Publisher
- Elsevier Science
- Year
- 1984
- Tongue
- English
- Weight
- 600 KB
- Volume
- 229
- Category
- Article
- ISSN
- 0003-9861
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
A series of analogs of 1 alpha,25-dihydroxyvitamin D3[1,25(OH)2D3] with alkyl substitutions in 26- and 27-positions were tested for calcium (Ca) regulating activity. The potencies of dialkyl analogs in stimulating bone resorption in neonatal mouse calvaria cultures were the highest in 1 alpha,25-dih
To determine the possibility that methyl substitution in 26- and 27-positions of 24R,25-dihydroxyvitamin D3 [24,25(OH)2D3] alters activities of the original compound, the effects of 24,25(OH)2D3 on calcium (Ca) regulating activity were compared with those of its methyl analog [24,25(OH)2(CH3)2D3] in