✦ LIBER ✦

160 Role of P53 status in radiation sensitivity and cell cycle progression

✍ Scribed by Richard C. Zellars; Tania Loney; Ann F. Schott; Mary A. Davis; Jonathan Maybaum; Michael F. Clarke; Theodore S. Lawrence

Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 88 KB
Volume: 32
Category: Article
ISSN: 0360-3016
DOI: 10.1016/0360-3016(95)97823-j

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

1045 Mutant p53 transfection of astrocyt

1045 Mutant p53 transfection of astrocytic cells results in altered cell cycle control, radiation sensitivity, and tumorigenicity

✍ Kirk E. Kanady; Mei Su; Gary Proulx; David M. Malkin; Francisco S. Pardo 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 106 KB

Characterisation of the P53 status, BCL-

Characterisation of the P53 status, BCL-2 expression and radiation and platinum drug sensitivity of a panel of human ovarian cancer cell lines

✍ Katharine E. Pestell; Clare J. Medlow; Jenny C. Titley; Lloyd R. Kelland; Michae 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 French ⚖ 124 KB 👁 2 views

The P53 gene is frequently mutated in late stage ovarian cancer and has been proposed as a determinant of radiation and chemosensitivity. We have therefore determined the p53 functional status, P53 sequence, radiation sensitivity and cytotoxicity of cisplatin and the novel platinum analogue, AMD473,

Selenoprotein W depletion induces a p53-

Selenoprotein W depletion induces a p53- and p21-dependent delay in cell cycle progression in RWPE-1 prostate epithelial cells

✍ Wayne Chris Hawkes; Ignat Printsev; Zeynep Alkan 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 264 KB

## Abstract The anticancer activity of selenium (Se) has been demonstrated in myriad animal and in vitro studies, yet the mechanisms remain obscure. The main form of Se in animal tissues is selenocysteine in selenoproteins, but the relative importance of selenoproteins versus smaller Se compounds i

A role for loss of p53 function in sensi

A role for loss of p53 function in sensitivity of ovarian carcinoma cells to taxanes

✍ Giuliana Cassinelli; Rosanna Supino; Paola Perego; Donatella Polizzi; Cinzia Lan 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 French ⚖ 302 KB 👁 1 views

Role of p53 status in chemosensitivity d

Role of p53 status in chemosensitivity determination of cancer cells against histone deacetylase inhibitor sodium butyrate

✍ Jeena Joseph; Narendra Wajapeyee; Kumaravel Somasundaram 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 French ⚖ 803 KB

## Abstract Histone deacetylases inhibitors (HDIs) induce growth arrest and apoptosis in a variety of human cancer cells. Sodium butyrate (NaB), a histone deacetylase inhibitor, has been shown to cause a G~1~ cell cycle arrest by inducing p21^WAF1/CIP1^ in a __p53__‐independent manner. In this repo

Effects of resveratrol analogs on cell c

Effects of resveratrol analogs on cell cycle progression, cell cycle associated proteins and 5fluoro-uracil sensitivity in human derived colon cancer cells

✍ Didier Colin; Amandine Gimazane; Gérard Lizard; Jean-Claude Izard; Eric Solary; 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 French ⚖ 601 KB

## Abstract Epidemiological studies suggested that __trans__‐resveratrol, a wine grape component, could prevent malignant tumor development. This compound also demonstrated cytostatic and cytotoxic effects on tumor cells __in vitro__. To obtain __trans__‐resveratrol derivatives with a better cellul