Insulin-like growth factor binding prote
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Constance J. Grill; Wendie S. Cohick
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Article
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2000
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John Wiley and Sons
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English
β 215 KB
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IGF-I is mitogenic for the bovine mammary epithelial cell line MAC-T. In addition, IGF-I specifically upregulates IGFBP-3 synthesis in these cells. To investigate this effect on cell growth and IGF-I responsiveness, cell lines were developed that constitutively express IGFBP-3. MAC-T cells transfect