1,6-dihydro-3(2H)-pyridinones as synthetic intermediates. Total synthesis of (±)-tecomanine
✍ Scribed by Takeshi Imanishi; Noriyuki Yagi; Miyoji Hanaoka
- Publisher
- Elsevier Science
- Year
- 1981
- Tongue
- French
- Weight
- 229 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
An asymmetric synthesis of 1-deoxynojirimycin (2) mediated by a chiral auxiliary is reported. The dihydropyridone 4 was converted to diol 11 in three steps by acetoxylation, hydrolysis, and stereoselective reduction. Dihydroxylation of 11 followed by catalytic reduction afforded 2.
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New derivatives of 1,2-dihydro-2-alkenyl-3H-pyrazoC 3-ones 6 and 7 have been synthesized at room temperature by a one-pot two-step reaction of PCZ,, a ketone methylhydrazone, and a f3-keto ester. With ketone methylhydrazones bearing at least a phenyl group in the a-positions to the C=N bond and in t