1,6-dihydro-3(2H)-pyridinones as synthetic intermediates. A novel total synthesis of (±)-ibogamine and (±)-epiibogamine
✍ Scribed by Takeshi Imanishi; Noriyuki Yagi; Hiroaki Shin; Miyoji Hanaoka
- Publisher
- Elsevier Science
- Year
- 1981
- Tongue
- French
- Weight
- 234 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0040-4039
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New derivatives of 1,2-dihydro-2-alkenyl-3H-pyrazoC 3-ones 6 and 7 have been synthesized at room temperature by a one-pot two-step reaction of PCZ,, a ketone methylhydrazone, and a f3-keto ester. With ketone methylhydrazones bearing at least a phenyl group in the a-positions to the C=N bond and in t
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More recently (q), CsF/Si(OCH3)4 was successfully used for 1,4-addition reactions to cr, B-unsaturated tertiary amides. We now report (see Table > the results 1311