## Abstract (1__R__,5__S__,6__S__)‐2‐ [(3__S__,5__S__)‐5‐Dimethylaminocarbonylpyrrolidin‐3‐ylthio]‐6‐ [(1__R__)‐1‐hydroxyethyl]‐1‐methylcarbapen‐2‐em‐3‐carboxylic acid trihydrate (SM‐7338), a novel 1 β‐methyl carbapenem antibiotic, was labeled with carbon‐14 at the C3 position of the carbapenem nuc
14C-labeling of a novel prostacyclin I1 derivative, SM-10902
✍ Scribed by Motohiro Kurosawa; Hiroshi Kanamaru; Kazuhiko Nishioka
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- French
- Weight
- 566 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
2S,3R)-2-[3-(4-Fluorophenyl)]propylamino-3-(3,4-di hydroxyphenyl)-3-hydroxypropionic acid pyrrolidine amide hydrobromide (SM-11044) was labeled with carbon-14 for use in mammalian metabolic studies. The synthesis was achieved according to the scheme shown in Fig. 5. Grignard reaction of 3,4-methylen
## Abstract An efficient protocol for the synthesis of ^14^C‐labeled 3‐pyridineacetate (**1**) and its __N__‐oxide ([^14^C]**2**) is described. Oxidation of this pyridine ([^14^C]**1**) to its __N__‐oxide ([^14^C]**2**) proceeded in high yield using H~2~O~2~ with MeReO~3~ as a catalyst. The reactio
## SUM MARY A ''C-labelled form of 2-chloro-K[(R)-(2-benzoxazolyl)thio-2-propyl]adenosine a, a novel antiischaemic adenosine A, agonist, has been prepared in three steps from [8- '4C]-9-(2,3,5-tri-0-benzoyl-~-D-ribofuranosyl)-2,6-dichloropurine a. The overall radiochemical yield was 56%. The radio
## Abstract Arg^34^Lys^26^(__N__^ε^‐(γ‐L‐glutamyl(__N__^α^‐palmitoyl)))‐GLP‐1(7‐37) (NN2211) is currently in development as a diabetes type 2 drug. The fatty acid attached to the GLP‐1(7‐37) ensures a long and controlled duration of action. The synthesis of [^125^I]NN2211, [^127^I]NN2211 and [^14^C
A novel fungicide, (-) (E)-1-( 2,4-di chlorophenyl)-4,4-dimethyl-2-(1,2,4-triazol-1-yl)-1-penten-3-ol (S-3308 L) and i t s three o p t i c a l l y active stereoisaners were labeled w i t h carbon-14 a t the t r i a z o l e r i n g f o r use i n the metabolic and environmental f a t e studies. 1 ,2,