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14.alpha.-Ethyl-5.alpha.-cholest-7-ene-3.beta.,15.alpha.-diol, an extraordinarily potent inhibitor of sterol biosynthesis in animal cells

✍ Scribed by Schroepfer, G. J.; Parish, E. J.; Kandutsch, A. A.


Book ID
127236596
Publisher
American Chemical Society
Year
1977
Tongue
English
Weight
412 KB
Volume
99
Category
Article
ISSN
0002-7863

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Inhibitors of sterol synthesis. Concerni
✍ Samuel T. Bowen; Edward J. Parish; William K. Wilson; George J. Schroepfer Jr.; 📂 Article 📅 1988 🏛 Elsevier Science 🌐 English ⚖ 399 KB

The chemical synthesis of 3 beta-p-bromobenzoyloxy-15 beta-methyl-5 alpha,14 beta-cholest-7-en-15 alpha-ol from 15 beta-methyl-5 alpha, 14 beta-cholest-7-ene-3 beta,15 alpha-diol is described. The structure of the former compound was unambiguously determined by X-ray crystallographic analysis. The s