1,4-Conjugate addition of higher-order cyanocuprates to 3-alkyl substituted 2(5H)-furanones
β Scribed by Felix S. Pashkovsky; Fedor A. Lakhvich; Alfredo Ricci; Mauro Comes-Franchini
- Book ID
- 119767896
- Publisher
- Royal Society of Chemistry
- Year
- 2001
- Tongue
- English
- Weight
- 89 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0959-9436
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π SIMILAR VOLUMES
## Abstract Benzonitrile oxide cycloadds to the Cο£ΎC bond of substituted 4,5βdihydroβ3βmethyleneβ2(3__H__)βfuranones 1aβ1g. Thus, (__E__)β1a and (__E__)β1b are converted into the corresponding isoxazolinespirodihydrofuranones (4__RS__,5__RS__)β2a and (4__RS__,5__RS__)β2b, and (__E__)β1c is converted
The synthesis of enantiomerically pure 5-menthyloxy-2(5B)-furanones is described as well as the diastereoselective 1,4-addition of thiols to these butenolides to yield new homochiral CQ-synthons. Kinetic resolution of 5-methoxy-2(5H)-furanone, with an enautiameric excess of 139, wae achieved by cinc