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1,4-Benzdiazepines and their derivatives III. Synthesis of derivatives of 1,3-dihydro-2H-1,4-benzdiazepin-2-one and correlation of structure with pharmacological activity

โœ Scribed by A. V. Bogatskii; Yu. I. Vikhlyaev; S. A. Andronati; T. A. Klygul'; T. K. Chumachenko; Z. I. Zhilina


Book ID
112489398
Publisher
Springer
Year
1970
Tongue
English
Weight
307 KB
Volume
4
Category
Article
ISSN
0091-150X

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Synthesis and pharmacological evaluation
โœ Franco De Marchi; Gian Franco Tamagnone; Mario V. Torrielli ๐Ÿ“‚ Article ๐Ÿ“… 1971 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 337 KB ๐Ÿ‘ 1 views

IJ Some 1,4-dihydre2H-3,1-benzoxa~in-2-one derivatives were synthesized and tested for pharmacological activity. CPhenyl-6-chloro-l,4-dihydro-2H-3,l-benzoxazin-2-one (Compound 4) exhibited anticonvulsant activity against chemically and electrically induced seizures and low acute toxicity in mice. St