The solution conformations and dynamics of the antidepressant drug trimipramine maleate were investigated by 'H and I3C NMR spectroscopy. Of particular interest was an observed non-equivalence of the N-methyl groups in the aliphatic sidechain of the drug, which is present in both 'H and I3C spectra
13C NMR studies of the molecular flexibility of antidepressants
β Scribed by Sharon L. Munro; Peter R. Andrews; David J. Craik; Douglas J. Gale
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 848 KB
- Volume
- 75
- Category
- Article
- ISSN
- 0022-3549
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