In diamonds unpaired electrons associated with nitrogen impurities can be used to enhance the 13C NMR signal via the solid-state effect. 13C spectra of three natural and two synthetic diamonds are shown that were obrained in this manner in lo-30 min.
13C MR reporter probe system using dynamic nuclear polarization
β Scribed by Albert P. Chen; Ralph E. Hurd; Yi-ping Gu; David M. Wilson; Charles H. Cunningham
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 540 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0952-3480
- DOI
- 10.1002/nbm.1618
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## Abstract ## Purpose: To present a method for significantly increasing the concentration of a hyperpolarized compound produced by a commercial dynamic nuclear polarization (DNP) polarizer, enabling the polarization process to be more suitable for preclinical applications. ## Materials and Metho
## Abstract Dynamic nuclear polarization of the coupled ^13^Cβ^l^H spin system was studied for optimizing the signalβtoβnoise ratio of __in vivo__ ^13^C MR spectra. In particular, the truncated driven and transient nuclear Overhauser effect (NOE) of the protonβdecoupled ^13^C resonances from methyl