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134: The role of Delta-40p53 and p53 in Estrogen Receptor-a signalling pathways in breast cancer

โœ Scribed by Morten, B.; Scott, R.J.; Avery-Kiejda, K.A.


Book ID
125797438
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
69 KB
Volume
50
Category
Article
ISSN
0959-8049

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A total of 76 primary breast cancers were screened for p53 mutations using the yeast p53 functional assay, and the mutations were determined by DNA sequencing. Clonal mutations of p53 were detected in 30 tumors (39%). Immunohistochemical staining for nuclear p53 accumulation performed on the yeast a